Strategy for the development of antibodies against ciguatoxins : bevetoxins as a model for polyether hydroxylated compounds.

3 Naar, J. Branaa, P. Dechraoui, M. Y. Chinain, M. Legrand, A-M. Pauillac, S. 2001 Strategy for the development of antibodies against ciguatoxins : bevetoxins as a model for polyether hydroxylated compounds. In : Harmful Algal Blooms, (Hallegraeff G.M., Blackburn S.I., Bolch C.J. and Lewis R.J., Eds). Intergovernmental Oceanographic Commission of UNESCO, pp 284-287 2001 As a model for hydroxylated polyether toxins, brevetoxin PbTx-3 was converted into a hemisuccinate derivative (PbTx-3 HS) and covalently linked to bovine serum albumin (BSA) and ovalbumin (OVA). By reacting a minute amount of PbTx-3 (0.446