The reversed micellar medium as a universal tool for the development of antibody-based assays to marine phycotoxins using small amount of toxic material.

3 Pauillac, S. Branaa, P. Chinain, M. Naar, J. 2001 The reversed micellar medium as a universal tool for the development of antibody-based assays to marine phycotoxins using small amount of toxic material. In : Harmful Algal Blooms, (Hallegraeff G.M., Blackburn S.I., Bolch C.J. and Lewis R.J., Eds). Intergovernmental Oceanographic Commission of UNESCO, pp 288-291 2001 The production of specific antibodies to marine phycotoxins is hampered by considerations such as toxicity, scarcity or chemical nature of these compounds. A rapid, simple and low cost procedure for preparing minute amount of hapten-protein immunogenic conjugates in a reversed micellar medium was successfully applied to purified toxins (0.32 - 0.64